Phenazepam is a profoundly sedative. By the power of sedating and anxiolytic (antianxiety) activity is better than other benzodiazepine sedatives and abenzodiazepinovye; It has additionally communicated an anticonvulsant, muscle relaxant (muscle-unwinding) and narcotic impact. When applied along with drugs and narcotic medications are collaborations discouraging impact on the focal sensory system.
Anxiolytic (sedative) benzodiazepine. It has anxiolytic, narcotic mesmerizing, anticonvulsant and focal muscle relaxant impact.
It builds the inhibitory impact of GABA in the transmission of nerve driving forces. It invigorates benzodiazepine receptors situated in the allosteric focal point of postsynaptic GABA receptors climbing enacting reticular development of the mind stem; lessens the sensitivity of the subcortical constructions of the cerebrum (the limbic framework, thalamus, nerve center), polisinapticheskie restrains spinal reflexes.
The anxiolytic impact is because of the effect on the amygdala of the limbic framework and shows itself in the decrease of passionate pressure, facilitating tension, dread, nervousness.
Sedation because of the impact on the reticular development of the cerebrum stem and the vague thalamic cores and showed a reduction in indications of hypochondriac beginning.
On the useful crazy indications beginning (intense silly, illusory, emotional issues) has for all intents and purposes no impact, it is seldom noticed reduction in full of feeling force, capricious issues.
Entrancing impacts related with hindrance of the cells of the reticular development of the cerebrum. Diminishes enthusiastic impacts, autonomic and engine improvements that upset rest.
Anticonvulsant activity is acknowledged by expanding presynaptic hindrance stifles the spread of seizure beat, yet doesn't dispose of the energized condition of the hearth.
Focal muscle relaxant impact is because of hindrance of polysynaptic spinal afferent inhibitory approaches (less significantly - and single reflex). Maybe, and direct restraint of engine nerve and muscle work.
Phenazepam Online select: at different hypochondriac, mental issues, psychopathic and psychopathic states, joined by uneasiness, dread, expanded peevishness, enthusiastic lability.
with fixations, fears hypochondriacal conditions (counting those impervious to the activity of different sedatives)
with psychogenic psychoses, alarm responses, and so on, since it eliminates the condition of tension and dread,
for alleviation (evacuation) of liquor withdrawal and insanity (state, coming about because of the unexpected suspension of liquor)
as an anticonvulsant and entrancing, for sedation during groundwork for careful activities.
When sleep disorders - 0.5 mg for 20-30 minutes before bedtime.
For the treatment of nevpoticheskih, psychopathic, and psihopatopodobnyh initial dose - 0.5-1 mg 2-3 times a day. After 2-4 days in view of efficacy and tolerability, the dose can be increased to 6.4 mg / day.
In severe agitation, fear, anxiety, treatment is initiated with a dose of 3 mg / day, quickly increasing the dose to produce a therapeutic effect.
In the treatment of epilepsy - 2.10 mg / day.
For the treatment of alcohol withdrawal - 2-5 mg / day.
The average daily dose - 1.5-5 mg, it is separated into 2-3 doses, usually 0.5-1 mg in the morning and afternoon, and 2.5 mg at night. In neurological practice for diseases with muscle hypertonicity appoint 2-3 mg 1-2 times a day.
The maximum daily dose - 10 mg.
In order to avoid the development of drug dependence at course treatment duration Phenazepam application is 2 weeks (in some cases the duration of treatment can be increased up to 2 months). If you cancel Phenazepam reduce the dose gradually.